Job Listings

Senior Scientist

Merck

Job Description

Position description:

The Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) function of our Research & Development Division South San Francisco is seeking a dynamic and collaborative scientist for the Drug Metabolism and Pharmacokinetics (DMPK) group. The Senior Scientist will be a member of the function providing expertise as a key component of the multi-disciplinary drug discovery effort in South San Francisco, with a focus on supporting preclinical development of therapeutics of various modalities through integrated understanding of drug disposition and pharmacology. Therapeutic areas may include immunology and oncology, cardiovascular and metabolic disease, and ophthalmology.

The Senior Scientist will work within teams of highly collaborative scientists to contribute to the characterization of novel therapeutic agents. The candidate will be responsible for independently planning and conducting in vitro/ex vivo studies to evaluate the DMPK properties of biologics. Ideal candidates will independently interpret data, clearly present data to teams, and integrate data to inform pipeline decisions. The candidate will contribute to scientific initiatives for further understanding in DMPK science.

The successful candidate should be an experienced scientist with knowledge and hands on expertise with biologics bioanalytical, cell based assays, etc. The Senior Scientist must be able to work collaboratively in a fast-paced environment and have excellent scientific, interpersonal, and communication skills.

Education Minimum Requirement:
• PhD in pharmaceutical sciences, Immunology, biology, biochemistry, chemistry, pharmacology, biochemical engineering or a related discipline.
• MS Degree with a minimum of 4 years of relevant experience.
• BS Degree with a minimum of 7 years of relevant experience

Required Experience and Skills:
• Demonstrated proficiency in design, performing, and interpreting cell based assays.
• Strong experience in experimentation science, including FACS, Elispot, ligand binding assay, etc.
• Highly motivated, self-driven and results-oriented individual with excellent communication and presentation skills
• An excellent team player that can closely collaborate with internal and external collaborators

Preferred Experience and Skills:
• Previous experience in drug discovery and development is a plus but not required
• General knowledge of PK, DMPK and/or drug discovery concepts
• Experience and knowledge in Immunology, predictive immunogenicity, including in silico analysis and in vitro assays, are plus but not required.
• High learning agility and a willingness to contribute to all levels within the DMPK group
• Demonstrated creativity and innovation via a publication/presentation record.
• Comfortable with risk taking and undertaking hypothesis-driven experimentation

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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Location: South San Francisco, CA

Posted: Aug. 20, 2024, 8:51 a.m.

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