Scientist, Antibody Drug Conjugates (ADCs) Bioconjugation
Gaithersburg, MD
Are you passionate about pushing the boundaries of science to change the practice of medicine? We are seeking a driven and proficient Scientist, Bioconjugation to join our Oncology R&D team. This role offers an exciting opportunity to spearhead and contribute to multifaceted drug development endeavors. Be part of a team that is dedicated to following the science and transforming the lives of patients living with cancer.
Accountabilities:
As a Scientist, you will be responsible for executing conjugation, purification, and characterization of Antibody Drug Conjugates (ADCs) and Radioconjugates (RCs). You will engage in cross-functional collaboration with diverse scientific teams to drive research progress and foster technological breakthroughs. Your role will also involve equipment maintenance and adherence to safety protocols.
Essential Skills/Experience:
• Master's degree in Organic Chemistry, Chemical Biology, Biochemistry, or related field with at least 4 years of relevant experience.
• Hands-on expertise in generating antibody drug conjugates.
• Proficiency in analytical characterization techniques such as Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid Chromatography–Mass Spectrometry (LC-MS), Ion-Exchange (IEX), and Reversed Phase (RP)-HPLC.
• Hands-on experience in protein purification using HIC, IEX, SEC, and affinity chromatography, preferably with GE AKTA FPLC.
• Consistent record of working autonomously, adeptly planning and organizing tasks, and prioritizing activities to meet project deadlines.
• Adept in protocol optimization and troubleshooting with a problem-solving approach, along with meticulous record-keeping in laboratory notebooks.
• Exceptional written and verbal communication skills, with the ability to convey complex scientific data effectively to cross-functional teams and senior management.
Desirable Skills/Experience:
• Experience with radioconjugates or radiolabeling is a plus.
• Experience in mammalian protein expression would be advantageous.
At AstraZeneca, we are united in our vision to eliminate cancer as a cause of death. We are pioneers, making bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
So, what’s next?
Are you ready to make a meaningful difference? Apply now!
If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.
Closing Date: September 10, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more-
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in emp
Location: Gaithersburg, MD
Posted: Aug. 15, 2024, 6:10 a.m.
Apply Now Company Website