Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Translational Medicine at BMS
Translational Medicine is part of the Global Research and Early Development organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late-stage portfolio for regulatory, translational development and life cycle management. Translational Medicine Hematology drives strategy for multiple disease areas of interest including Multiple Myeloma, Lymphoma, CLL, AML, MDS, anemias and other hematological malignancies. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics.
Summary
Working within Translational Medicine Team, the candidate will be part of the translational group based in Summit NJ and will contribute to/manage the scientific and preclinical laboratory component of late-stage hematology programs (phase 2 and beyond). Key responsibilities of this role are to lead from the bench for the preclinical support of asset programs through mechanism of action-based studies, differentiation from standard of care molecules, combination rationale and resistance mechanisms. He/She will work with translational scientists, disease leaders within translational medicine and thematic research centers in early development within the company.
Responsibilities
• Conduct preclinical/laboratory research to support late-stage BMS compounds. Contribute to achieving the annual goals and objectives of the Hematology Translational Medicine group, including internal and external collaborations and compound-specific plans.
• Responsible for delivering data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms, drug differentiation and therapeutic target identification/validation
• Interfaces with other research scientists within and outside of the Heme TMDT group to ensure seamless flow of information for assets which are entering the remit of translational medicine
• Communicates regularly and prepares and makes presentations within the department
The successful candidate will have:
• Extensive experience in handling and maintaining mammalian cells.
• Research experience in the field of molecular/cell/cancer biology, translational research, or another relevant field
• Solid scientific background in understanding and performing cell-based assays and readouts
• Capable of critical and creative thinking across various disciplines. Proven problem-solving skills in research, including experience with standard in vitro assays, assay development, optimization, and troubleshooting
• Ability to multitask and effectively collaborate with a diverse team of scientists to achieve results and meet stakeholder needs
• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications
Basic Qualifications:
• Bachelor's Degree with 5+ years of academic and / or industry experience
Or
• Master's Degree with 3+ years of academic and / or industry experience
Or
• Ph.D. or equivalent advanced degree in the Life Sciences
Preferred Qualifications:
• In-depth understanding of cancer biology (hematology a plus) and evolving technologies
• Extensive hands-on experience with molecular and cellular biology techniques and cell-based assays, including but not limited to: DNA/RNA purification, qPCR, flow cytometry, Western blotting, capillary Western blotting, InCucyte, MSD/ELISA, RNAi, CRISPR/Cas9-mediated gene editing, and drug combination assays
• Experience with next-generation sequencing and single-cell sequencing technologies is a plus
• Experience in isolating Monocytes, T-cells and NK cells from PBMCs is a plus
• Strong ability to troubleshoot and optimize novel methods and protocols
• Good understanding of drug development process in an industry setting with clear examples of success
• Understanding of late-stage drug a
Location: Summit, NJ
Posted: Oct. 21, 2024, 9:23 p.m.
Apply Now Company Website