Job Description
Our Company is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. The Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) function of our Research & Development Division in West Point, Pennsylvania, is seeking a highly skilled and motivated Scientist to join the Transporter Science Group. The Transporter Science group is a center of excellence to design, execute, and integrate transporter related in vitro and preclinical studies to support our Company Portfolio through all stages of drug discovery and development. We are also driving cutting edge ADME-transporter science via development and implementation of novel in vitro and preclinical models, as well as translational approaches to enhance our capabilities to quantitatively predict the roles of transporters on ADME, drug-drug interactions (DDIs), efficacy, and toxicity of drugs in a diversified portfolio that spans various therapeutic areas and modalities.
In this position, candidates will be responsible to generate transporter related in vitro data to support discovery and development programs. Candidates will also have the opportunity to work closely with other scientists across the network to advance our scientific strategy via developing and implementing novel tools/emerging technologies. Successful candidates should have a passion for generating high quality data for use by project teams across a range of therapeutic areas and must be able to work independently with a range of in vitro assay systems. In addition, candidates will be conducting experiments using automated liquid handlers and other sophisticated scientific instrumentation. Candidates must have excellent written and verbal communications and experience working in a team environment.
Position Qualifications:
Education Minimum Requirement:
• A master’s or bachelor’s degree in a relevant field (e.g. Biochemistry, Biology, Biotechnology, Molecular and Cell Biology, Pharmacology; Pharmaceutical Sciences) with relevant laboratory experience.
Required Experience and Skills:
• Cell culture, including aseptic techniques and maintenance of recombinant cell lines and primary cells
• Demonstrated ability to design, perform and interpret in vitro studies generated in cell lines, hepatocytes or subcellular fractions per established protocols
• Ability to work independently and effectively to develop and validate new assays with some technical and strategic supervision
• Proficiency in data handling software such as Excel and Graphpad, ability to document results accurately and generate reports to be shared with internal partners or regulatory agencies
• Strong communication and collaboration skills with flexibility to operate in a team environment
• Autonomy, attention to details, critical thinking, and growth mindset
Preferred Experience and Skills:
• Experience with assay automation and operation of liquid handlers
• Experience and /or knowledge with transporter and enzyme related studies
• Basic understanding of quantitation using radiometric or LC/MS methods
• Experience working in the pharmaceutical industry or contract research organizations
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role pre
Location: West Point, PA
Posted: Aug. 15, 2024, 6:10 a.m.
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